To apply for a multiple-entry visa to the United States, you will need to follow these general steps:

1. Determine your visa type: You must first determine which type of visa you need to apply for. The most common visa for tourism or business is the B1/B2 visa.
2. Complete the online application: Fill out the online nonimmigrant visa application form (DS-160) on the U.S. Department of State website.
3. Pay the visa application fee: The application fee varies depending on the type of visa you are applying for. You can pay the fee online or at a designated bank.
4. Schedule an interview: Schedule an appointment at the U.S. embassy or consulate in your country for a visa interview. Wait times for appointments vary depending on the location and time of year.
5. Prepare for the interview: Gather all required documents, including your passport, DS-160 confirmation page, photograph, and any additional documentation related to your purpose of travel. Be prepared to answer questions about your intended activities in the U.S. and your ties to your home country.
6. Attend the interview: On the day of your interview, arrive early and bring all required documents. Be prepared to answer any additional questions the consular officer may have.
7. Wait for a decision: After the interview, you will be informed if your application is approved, denied, or requires further administrative processing.

If your application is approved, you will receive your multiple-entry visa within a few days or weeks, depending on the processing times at the embassy or consulate.